Johnson & Johnson has found itself on the losing end of multi-million dollar awards in lawsuits filed by victims who used Motrin and suffered the sometimes fatal skin reaction known as toxic epidermal necrolysis (TEN).

In 2011, a California jury awarded $48 million to a man who sued Johnson & Johnson and McNeil Consumer & Specialty Pharmaceuticals, a J&J subsidiary, for developing TEN after taking Motrin. Christopher T.’s Motrin product liability lawsuit claimed that the drug’s warning label should have alerted consumers to the risk of an extreme reaction.

When he was 16, Christopher suffered Stevens Johnson Syndrome, and its more severe variation, toxic epidermal necrolysis, after taking the pain reliever for aches and pains.

Christopher allegedly suffered pulmonary damage, near blindness and hypoxic brain injury as a result of complications caused by the syndrome.

The jury award included more than $15 million in punitive damages, more than $11 million for the cost of future medical expenses and future lost earnings, and $22 million in non-economic damages, including mental suffering and pain.

A higher court denied J&J’s appeal, finding that the over-the-counter version of Motrin should have contained an explicit warning about the potential skin reactions, just as it had for prescription Motrin, indicating the company was aware of the risk.

The U.S. Food and Drug Administration (FDA) has since required that over-the-counter Motrin labels contain more explicit information about Stevens Johnson Syndrome and toxic epidermal necrolysis.

In 2013, a Massachusetts jury awarded the family of a 7-year-old girl $63 million — $50 million for the child and $6.5 million for each parent — after Samantha R. suffered toxic epidermal necrolysis caused by Children’s Motrin. Jurors found that Johnson & Johnson failed to adequately warn about the painkiller’s potential side effects.

When she developed a fever on Thanksgiving 2003, Samantha was given Children’s Motrin. Despite continuing to take the medication, her condition worsened, the Boston Globe reported.

Doctors determined within days that Samantha was suffering from TEN, the most severe form of Stevens-Johnson Syndrome.

Samantha reportedly spent months in and out of the hospital, underwent multiple surgeries, lost nearly all her skin, suffered permanent lung and liver damage, and could not walk more than 150 yards without exhaustion, according to the Globe. Samantha is now a legally blind teenager.

SJS presents with flu-like symptoms, followed by a potentially life-threatening skin disease with a rash similar to a burn, open sores and skin peeling. Other signs of the disease include a purplish rash, painful blisters of the mucus membranes, blisters on the eyes, nose, mouth, and genitals, sloughing off of skin in large patches, joint and muscle pain and a burning sensation all over the body. It is sometimes described as the skin burning from the inside out.

Its more severe form, TEN, is diagnosed when blisters meld and cover 30 percent or more of the body. The skin also peels off in layers, exposing the skin’s under layer, the dermis, and making the body ripe for infection.

Between 5 percent and 15 percent of SJS patients die from the side effects, while about up to 40 percent of TEN patients succumb to the disease. Those who survive risk myriad medical problems including a secondary skin infection (cellulitis), sepsis, blindness, internal organ damage and permanent skin damage.