Using contrast during magnetic resonance imaging (MRI) scans may be unsafe due to adverse reactions and gadolinium retention for years after the initial scan. With some 8.8 million MRI procedures using gadolinium-based contrast agents (GBCDs) performed in the U.S. in 2016 alone, gadolinium retention could be cause for concern for many Americans, according to JAMA.

What Is MRI Contrast?

Gadolinium-based contrast agents may be used during MRI scans to improve the visualization of the body’s structures. Gadolinium is a chemical element often used in these contrast agents to provide clearer imaging, which in turn helps diagnose and monitor a number of health conditions, including cancer.

Notably, gadolinium is toxic to humans. When used in GBCDs, however, the gadolinium goes through a process called chelation that is supposed to make it non-toxic and safe for use in the human body.

Contrast in MRI scans is administered during the procedure through an IV with the injection taking between 10 and 30 seconds. Most patients reportedly experience no sensations after injection, although some may notice a cold feeling in their arm. Other reactions like nausea, headaches, and vomiting are rarer but can occur.

MRI images are made from various shades of gray determined by the MRI signal given off by the tissue during a scan. This means that some tissues may appear very similar. The gadolinium in contrast agents helps to enhance these images by virtue of being a heavy metal. As a result, tissues appear as glowing a bright white. The contrast helps increase the detail of images.

Why Is Contrast Used In MRI?

Contrast agents may be used during an MRI if the doctor orders it. Because these agents can enhance image quality, contrast may be used when looking at tumors, inflammation, blood supply, blood vessels, and other features that require fine details.

Gadolinium contrast agents are reportedly used in about one of every three MRI scans.

Is Contrast in MRI Dangerous?

Ideally, contrast in MRI scans is filtered out of the bloodstream through the kidneys in the days following the imaging. Some patients, however, may retain gadolinium contrast dye in their body for years after an MRI scan, something that can reportedly lead to a variety of side effects.

Gadolinium retention occurs mostly in the bones, but the heavy metal can also be retained in the brain.

The most dangerous and notable consequence of MRI contrast agents is a condition known as nephrogenic systemic fibrosis (NSF). This condition is relatively rare and reportedly results in thickening skin, painful joint contractures, and fibrosis (scarring) of the lungs, liver, muscles, heart, and other organs.

NSF reportedly occurs most commonly in patients with poor kidney function, leading to the contrasts not being recommended for at-risk patients. However, some people with normal kidney function claim to have experienced the issue.

In December 2017, the U.S. Food and Drug Administration (FDA) recognized the risk for gadolinium retention and approved a new warning for all gadolinium contrast agents to inform patients of the risks.

In a May 2018 update, the FDA also approved new patient medication guides to be given to patients the first time they receive a gadolinium contrast injection, or if the information in the guide has “substantially changed.” This differs from other medication guides which are not required unless a patient or caregiver specifically requests it.

Although the agency recognized these risks and required new warnings, it did not implement any further action after “conclud[ing] that the benefit of all approved GBCAs continues to outweigh any potential risks.”

Filing a Gadolinium MRI Lawsuit

A growing number of people are coming forward with claims that they suffered from side effects related to gadolinium retention after a gadolinium-based contrast agent was used during their MRI.

If you or someone you love has suffered from side effects of gadolinium retention, such as gadolinium toxicity or poisoning, you may be able to file a lawsuit and pursue compensation. Filing a lawsuit cannot take away the pain and suffering caused by these complications, but it can at least help to alleviate the financial burden incurred by medical expenses, lost wages, and more.

Filing a lawsuit can be a daunting prospect, so Top Class Actions has laid the groundwork by connecting you with an experienced attorney. Consulting an attorney can help you determine if you have a claim, navigate the complexity of litigation, and maximize your potential compensation.