Patients have complained of adverse effects and complications suffered after receiving eye injections of Avastin, also known as bevacizumab. The issues that arise with Avastin eye injections are often not due to the drug itself but instead are linked to the delivery method of the drug.
Avastin injection side effects have been linked to the way the drug is placed into syringes used for injection. Before a patient is injected with Avastin, the drug is placed into a syringe that may be lubricated with silicone oil. This is done by compound pharmacists.
The silicone oil has been found to make its way and mix in with the drug, causing silicone floaters in patients’ eyes. These floaters may look a lot like air bubbles to a patient that has been injected with Avastin.
Avastin Injection Side Effects
Avastin injection side effects have been linked to other complications such as inflammation; corneal damage; vision loss/blindness; hypotony, or reduced pressure in the eye; glaucoma, or increased pressure in the eye; retinal detachment; retinal tearing; increased intraocular pressure; and infection.
Avastin injection side effects have resulted from this Avastin cancer treatment drug. Avastin has been prescribed to treat eye-related diseases such as diabetic retinopathy; retinal vein occlusion; diabetic mcular edema; and macular degeneration.
There are off-label uses of the drug that have not been specifically approved by the U.S. Food and Drug Administration (FDA). Medical practitioners are permitted to prescribe off-label uses of the medication, even though Avastin has not undergone full FDA review for these uses. It is, however, illegal for pharmaceutical companies to promote off-label uses that have not been approved by the FDA.
How Avastin Injection Side Effects Occur
To prepare Avastin for use as a treatment for eye diseases, it must be first placed into a syringe by a compounding pharmacy. A syringe filled with the Avastin drug is then sent off to an ophthalmologist.
Problems that arise with the Avastin drug is what happens to the drug after it is placed in the syringe. Once the drug is placed into the syringe, the silicone oil used to lubricate the syringe may migrate to the surface of the syringe and come in contact with the plunger, needle, and barrel, potentially contaminating the medication inside the syringe.
The longer it takes for the syringe to be used, the higher the likelihood of the silicone oil mixing in with the Avastin drug. Freezing the syringe before use also increases the chances of the two mixing together. When the syringe is used to inject Avastin into the patient’s eye, droplets of silicone oil may form visible floaters.
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