Who’s Affected?

diabetic amputations linked to diabetes drugsDid you or a loved one suffer side effects after taking the diabetes drugs Jardiance or Farxiga?

Did you know that these drugs have been linked to the very side effect they are meant to prevent – diabetes amputation?

A recently published study has revealed a link between an increased risk of diabetes amputation and the diabetes drugs Jardiance and Farxiga. In addition, case reports to the U.S. Food and Drug Administration indicate that these drugs are resulting in side effects for patients with diabetes.

Farxiga, a sodium-glucose cotransporter-2 (SGLT2) inhibitor also known as dapagliflozin, is manufactured by AstraZeneca. Jardiance (empagliflozin) is also an SGLT2 inhibitor and is made by Boehringer Ingelheim/Eli Lilly.

Until this study, the diabetes drugs Invokana, Invokamet, and Invokamet XR, also sodium-glucose cotransporter-2 (SGLT2) inhibitors, had been associated with an increased risk of amputation. However, researchers concluded after the study that the use of Jardiance and Farxiga were also associated with amputations of toes, feet, and even lower legs in diabetes patients.

Those at higher risk for diabetes amputations while taking the drugs include older men who carry excess weight and those with peripheral artery disease or foot ulcers.

If you or a loved one had to undergo diabetic amputation of the toe, foot, knee or leg after taking Farxiga or Jardiance, you may have a legal claim.

Fill out the FREE form on this page for more information. 

Overview: Jardiance, Farxiga Diabetes Amputation and Other Side Effects

The study, published in BMJ, used registry data from Swedish and Danish health and administrative databases from 2013 through 2016. Researchers found that those treated with Jardiance or Farxiga were twice as likely to require a lower limb amputation as patients treated with other medications, known as GLP1 drugs.

While the FDA had released a warning about diabetic amputation related to canagliflozin, no warning has been issued for Jardiance or Farxiga side effects. Canagliflozin includes Invokana and Invokamet. The recently released Swedish study is the first research on patients primarily taking Jardiance or Farxiga. Of the over 17,000 patients studied, 61 percent were taking Farxiga and 38 percent were on Jardiance to control their diabetes.

While experts stress the need for additional research, it appears that diabetes patients at higher risk for amputation should take precautions.

“As for lower-limb amputation, our findings should lead to further emphasis on the importance of counseling patients on routine preventative foot care,” noted one of the researchers.

Patients at high risk for diabetes amputation while taking Jardiance or Farxiga include older, obese males. Additionally, those with circulation problems, like peripheral artery disease, may also be at higher risk of Farxiga or Jardiance side effects.

According to WebMD, poor circulation increases the risk of diabetes amputation because of the way Jardiance and Farxiga, both SGLT2 inhibitors, work. The drugs work by causing the patient to excrete more sugar in their urine. This may cause the patient to urinate more, become dehydrated, ultimately decreasing blood volume. Those with poor circulation may be additionally compromised because of the decrease.

Read more: What Are The Side Effects Of Taking Farxiga?

Jardiance and Farxiga Side Effects

In addition to diabetes amputation, both drugs have been associated with additional Jardiance and Farxiga side effects, including diabetic ketoacidosis, acute kidney injury, and serious urinary tract infection. Researchers found that the rate of diabetic ketoacidosis doubled for those taking the drugs.

Among the Farxiga and Jardiance side effects, diabetic ketoacidosis is one of the most dangerous. Patients suffering from this side effect face a life-threatening buildup of acids, called ketones, in the bloodstream.

Diabetes drugs like Jardiance and Farxiga are meant to help patients avoid lower limb amputations, but, as this study reveals, they may be facing an increased risk. Drug makers make billions of dollars from these products, and patients, along with their physicians, need to be aware of the risks so they can decide if the drug is right for them. However, if the drug companies fail to include warnings about the risk of diabetic amputation or other Farxiga or Jardiance side effects, then a patient may be unknowingly placed at risk of injury or even death.

Filing a Jardiance Lawsuit or a Farxiga Lawsuit

The Swedish study reported a potential link between an increased risk of diabetic amputation and the drugs Farxiga and Jardiance. Patients who suffered diabetic amputation after taking these drugs may not have known of the risk. Further, the doctors of patients at high risk for diabetic amputation may not have been warned to use an alternative drug or, at a minimum, take additional care.

“[P]atients at high risk of amputation—for example, such as those with peripheral artery disease or foot ulcers—might be monitored more closely if SGLT2 inhibitors are used,” stated one of the study authors.

Before a drug goes to market, it should be rigorously tested to ensure any harmful side effects are disclosed. These side effects are generally disclosed on a drug’s warning label, so patients and their doctors can adequately assess the risk. However, if appropriate tests were not performed prior to release of the drug or if drug companies hid findings of negative side effects, proper warnings may not be included on a drug’s label.

If it can be demonstrated that the makers of Farxiga, AstraZeneca, or Jardiance, Boehringer Ingelheim/Eli Lilly, failed to disclose the risk of diabetic amputation, then they may be responsible for the pain and suffering of patients taking their drugs.

If you or a loved one experienced diabetes amputation after taking Jardiance or Farxiga, you may have a legal claim and may be eligible to seek compensation from the drug maker for your medical and other expenses. Fill out the form on this page now to see if you qualify!

[NOTE: Invokamet and Invokana users who suffered lower limb amputation may qualify to join a separate class action lawsuit investigation here.]

Get Help – It’s Free

Join a Free Jardiance, Farxiga Diabetes Amputation Class Action Lawsuit Investigation

If you qualify, an attorney will contact you to discuss the details of your potential case at no charge to you.

If you took Invokana or Invokamet, you do not qualify for this investigation. Click here to join a separate class action lawsuit investigation.

PLEASE NOTE: If you want to participate in this investigation, it is imperative that you reply to the law firm if they call or email you. Failing to do so may result in you not getting signed up as a client or getting you dropped as a client.

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After you fill out the form, the diabetes amputation attorneys who work with Top Class Actions will contact you if you qualify to let you know if an individual lawsuit or class action lawsuit is best for you.


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